College Football Week 5 Odds and Betting Trends

Special to Outkick The Coverage from OddsShark.com

The key ACC matchup will pit Clemson quarterback Deshaun Watson against Louisville counterpart Lamar Jackson, who has emerged as the early favorite to win the Heisman. Watson was one of the preseason favorites along with Stanford Cardinal running back Christian McCaffrey.

The Tigers have won 18 straight home games according to the OddsShark College Football Database, going 10-8 against the spread during that stretch, including 1-4 in their past five.

The Cardinals have gone 10-2 SU in their last 12 games when losing the previous meeting in a series, and they are 4-0 SU and ATS in their previous four after consecutive wins. Louisville has lost the past two meetings with Clemson but covered the spread both times.

In the Big Ten, a Top-10 matchup between the Wisconsin Badgers (4-0) and the Michigan Wolverines (4-0) will also take place in Ann Arbor on Saturday. The Badgers are 7-1-1 ATS in the previous nine meetings with the Wolverines, who are listed as 10.5-point home chalk. Michigan has gone 9-2 SU in its last 11 games versus teams with winning records.

Other college football Week 5 odds and betting trends:

Tennessee (-3.5) at Georgia

Tennessee is 6-1 ATS in its last seven games against SEC opponents.

Georgia is 5-1 SU in its last six games versus Tennessee.

Texas at Oklahoma State (-3)

The visiting team is 9-0 ATS in its last nine games in this matchup.

Oklahoma State is 1-5 SU and ATS in its last six games against teams with winning records.

Oklahoma (-3.5) at TCU

Oklahoma is 0-3 ATS in its last three games versus TCU.

TCU is 7-0 SU in its last seven games after losing the previous game in a matchup.

North Carolina at Florida State (-11)

The visiting team is 5-0 ATS in its last five games in this matchup.

Florida State is 7-3 ATS in its last 10 games.

Kentucky at Alabama (-34.5)

Kentucky is 1-5 SU and ATS in its last six games against teams with winning records.

Alabama is 16-0 SU and 10-6 ATS in its last 16 games overall.

Written by
Clay Travis is the founder of the fastest growing national multimedia platform, OutKick, that produces and distributes engaging content across sports and pop culture to millions of fans across the country. OutKick was created by Travis in 2011 and sold to the Fox Corporation in 2021. One of the most electrifying and outspoken personalities in the industry, Travis hosts OutKick The Show where he provides his unfiltered opinion on the most compelling headlines throughout sports, culture, and politics. He also makes regular appearances on FOX News Media as a contributor providing analysis on a variety of subjects ranging from sports news to the cultural landscape. Throughout the college football season, Travis is on Big Noon Kickoff for Fox Sports breaking down the game and the latest storylines. Additionally, Travis serves as a co-host of The Clay Travis and Buck Sexton Show, a three-hour conservative radio talk program syndicated across Premiere Networks radio stations nationwide. Previously, he launched OutKick The Coverage on Fox Sports Radio that included interviews and listener interactions and was on Fox Sports Bet for four years. Additionally, Travis started an iHeartRadio Original Podcast called Wins & Losses that featured in-depth conversations with the biggest names in sports. Travis is a graduate of George Washington University as well as Vanderbilt Law School. Based in Nashville, he is the author of Dixieland Delight, On Rocky Top, and Republicans Buy Sneakers Too.